Clostridioides difficile infection, recurrence and the associated healthcare consumption in Sweden between 2006 and 2019: a population-based cohort study | BMC Infectious Diseases

Clostridioides difficile infection, recurrence and the associated healthcare consumption in Sweden between 2006 and 2019: a population-based cohort study | BMC Infectious Diseases

  • Magill SS, O’Leary E, Janelle SJ, Thompson DL, Dumyati G, Nadle J, et al. Changes in prevalence of health care–associated infections in US hospitals. N Engl J Med. 2018;379(18):1732–44.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Finn E, Andersson FL, Madin-Warburton M. Burden of Clostridioides difficile infection (CDI) – a systematic review of the epidemiology of primary and recurrent CDI. BMC infectious diseases. 2021;21(1):456 PubMed PMID: 34016040. Pubmed Central PMCID: PMC8135979. Epub 2021/05/22. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Borren NZ, Ghadermarzi S, Hutfless S, Ananthakrishnan AN. The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact. PloS one. 2017;12(5):e0176797.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ghia CJ, Waghela S, Rambhad GS. Systematic Literature Review on Burden of Clostridioides difficile Infection in India. Clinical pathology (Thousand Oaks, Ventura County, Calif). 2021;14:2632010×211013816 PubMed PMID: 34104883. Pubmed Central PMCID: PMC8170333. Epub 2021/06/10. eng.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Balsells E, Shi T, Leese C, Lyell I, Burrows J, Wiuff C, et al. Global burden of Clostridium difficile infections: a systematic review and meta-analysis. J Glob Health. 2019;9(1):010407. Epub 2019/01/04. eng.

  • Boven A, Vlieghe E, Engstrand L, Andersson FL, Callens S, Simin J, Brusselaers N. Clostridioides difficile infection-associated cause-specific and all-cause mortality: a population-based cohort study. Clin Microbiol Infect. 2023:S1198-743X(23):00315–4. Epub ahead of print.

  • Yu H, Flaster N, Casanello AL, Curcio D. Assessing risk factors, mortality, and healthcare utilization associated with Clostridioides difficile infection in four Latin American countries. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. 2021;25(1):101040.

    Article 
    PubMed 

    Google Scholar 

  • Malone DC, Armstrong EP, Gratie D, Pham SV, Amin A. A systematic review of real-world healthcare resource use and costs of Clostridioides difficile infections. Antimicrobial stewardship & healthcare epidemiology : ASHE. 2023;3(1):e17.

    Article 
    PubMed Central 

    Google Scholar 

  • Reveles KR, Yang M, Garcia-Horton V, Edwards ML, Guo A, Lodise T, et al. Economic Impact of Recurrent Clostridioides difficile Infection in the USA: A Systematic Literature Review and Cost Synthesis. Advances in therapy. 2023;40(7):3104–34 PubMed PMID: 37210680. Pubmed Central PMCID: PMC10272265. Epub 2023/05/21. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wingen-Heimann SM, Davies K, Viprey VF, Davis G, Wilcox MH, Vehreschild M, et al. Clostridioides difficile infection (CDI): A pan-European multi-center cost and resource utilization study, results from the Combatting Bacterial Resistance in Europe CDI (COMBACTE-CDI). Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2023;29(5):651.e1-e8 PubMed PMID: 36586512. Epub 2023/01/01. eng.

    Article 
    PubMed 

    Google Scholar 

  • Zhang S, Palazuelos-Munoz S, Balsells EM, Nair H, Chit A, Kyaw MH. Cost of hospital management of Clostridium difficile infection in United States-a meta-analysis and modelling study. BMC infectious diseases. 2016;16(1):447 PubMed PMID: 27562241. Pubmed Central PMCID: PMC5000548. Epub 2016/08/27. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Nanwa N, Sander B, Krahn M, Daneman N, Lu H, Austin PC, et al. A population-based matched cohort study examining the mortality and costs of patients with community-onset Clostridium difficile infection identified using emergency department visits and hospital admissions. PloS one. 2017;12(3):e0172410. PubMed PMID: 28257438. Pubmed Central PMCID: PMC5336215. Epub 2017/03/04. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Shorr AF, Zilberberg MD, Wang L, Baser O, Yu H. Mortality and Costs in Clostridium difficile Infection Among the Elderly in the United States. Infect Control Hosp Epidemiol. 2016;37(11):1331–6 PubMed PMID: 27572289. Epub 2016/10/22. eng.

    Article 
    PubMed 

    Google Scholar 

  • Braae UC, Møller FT, Ibsen R, Ethelberg S, Kjellberg J, Mølbak K. The Economic Burden of Clostridioides difficile in Denmark: A Retrospective Cohort Study. Frontiers in public health. 2020;8:562957. PubMed PMID: 33324595. Pubmed Central PMCID: PMC7725905. Epub 2020/12/17. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Son KJ, Kim YA, Park YS. Economic burden attributable to Clostridioides difficile infections in South Korea: a nationwide propensity score-matched study. The Journal of hospital infection. 2022;120:1–8 PubMed PMID: 34774670. Epub 2021/11/15. eng.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Kuntz JL, Baker JM, Kipnis P, Li SX, Liu V, Xie Y, et al. Utilization of Health Services Among Adults With Recurrent Clostridium difficile Infection: A 12-Year Population-Based Study. Infect Control Hosp Epidemiol. 2017;38(1):45–52 PubMed PMID: 27760583. Pubmed Central PMCID: PMC5532139. Epub 2016/10/21. eng.

    Article 
    PubMed 

    Google Scholar 

  • Graves N, Harbarth S, Beyersmann J, Barnett A, Halton K, Cooper B. Estimating the cost of health care-associated infections: mind your p’s and q’s. Clin Infect Dis. 2010;50(7):1017–21.

    Article 
    PubMed 

    Google Scholar 

  • Sahrmann JM, Olsen MA, Stwalley D, Yu H, Dubberke ER. Costs Attributable to Clostridioides difficile Infection Based on the Setting of Onset. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023;76(5):809–15 PubMed PMID: 36285546. Pubmed Central PMCID: PMC10226732. Epub 2022/10/27. eng.

    Article 
    PubMed 

    Google Scholar 

  • Sahrmann JM, Olsen MA, Keller MR, Yu H, Dubberke ER. Healthcare Costs of Clostridioides difficile Infection in Commercially Insured Younger Adults. Open forum infectious diseases. 2023;10(7):ofad343 PubMed PMID: 37496610. Pubmed Central PMCID: PMC10368308. Epub 2023/07/27. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Durovic A, Widmer AF, Frei R, Tschudin-Sutter S. Distinguishing Clostridium difficile Recurrence From Reinfection: Independent Validation of Current Recommendations. Infect Control Hosp Epidemiol. 2017;38(8):891–6 PubMed PMID: 28592348. Epub 2017/06/09.

    Article 
    PubMed 

    Google Scholar 

  • Moreels N, Boven A, Gressani O, Andersson FL, Vlieghe E, Callens S, et al. The combined effect of systemic antibiotics and proton pump inhibitors on Clostridioides difficile infection and recurrence. The Journal of antimicrobial chemotherapy. 2024;79(3):608–16 PubMed PMID: 38267263. Pubmed Central PMCID: PMC10904719. Epub 2024/01/25.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Mpakaniye P, Boven A, Callens S, Engstrand L, Vlieghe E, Brusselaers N. Clostridioides difficile recurrence in individuals with and without cancer: a Swedish population-based cohort study. Infection. 2024;52(2):649–60 PubMed PMID: 38407777. Pubmed Central PMCID: PMC10954957. Epub 2024/02/26.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wettermark B, Hammar N, Fored CM, Leimanis A, Otterblad Olausson P, Bergman U, et al. The new Swedish Prescribed Drug Register–opportunities for pharmacoepidemiological research and experience from the first six months. Pharmacoepidemiology and drug safety. 2007;16(7):726–35 PubMed PMID: 16897791. Epub 2006/08/10. eng.

    Article 
    PubMed 

    Google Scholar 

  • Ludvigsson JF, Otterblad-Olausson P, Pettersson BU, Ekbom A. The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research. European journal of epidemiology. 2009;24(11):659–67 PubMed PMID: 19504049. Pubmed Central PMCID: PMC2773709.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Brusselaers N, Lagergren J. The Charlson Comorbidity Index in Registry-based Research. Methods Inf Med. 2017;56(5):401–6 PubMed PMID: 29582935.

    Article 
    PubMed 

    Google Scholar 

  • Nelson WW, Scott TA, Boules M, Teigland C, Parente A, Unni S, et al. Health care resource utilization and costs of recurrent Clostridioides difficile infection in the elderly: a real-world claims analysis. J Manag Care Spec Pharm. 2021;27(7):828–38 PubMed PMID: 33703939.

    PubMed 

    Google Scholar 

  • Nordling S, Anttila VJ, Noren T, Cockburn E. The Burden of Clostridium Difficile (CDI) Infection in Hospitals, in Denmark, Finland, Norway And Sweden. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2014;17(7):A670 PubMed PMID: 27202459. Epub 2014/11/01. eng.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • van Rossen TM, Ooijevaar RE, Vandenbroucke-Grauls C, Dekkers OM, Kuijper EJ, Keller JJ, et al. Prognostic factors for severe and recurrent Clostridioides difficile infection: a systematic review. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2022;28(3):321–31 PubMed PMID: 34655745. Epub 2021/10/17. eng.

    Article 
    PubMed 

    Google Scholar 

  • Singh H, Nugent Z, Walkty A, Yu BN, Lix LM, Targownik LE, et al. Direct cost of health care for individuals with community associated Clostridium difficile infections: A population-based cohort study. PloS one. 2019;14(11):e0224609. Epub 2019/11/09. eng.

  • Ludvigsson JF, Andersson E, Ekbom A, Feychting M, Kim JL, Reuterwall C, et al. External review and validation of the Swedish national inpatient register. BMC Public Health. 2011;11:450 PubMed PMID: 21658213. Pubmed Central PMCID: 3142234. Epub 2011/06/11. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Forsberg L RH, Jacobsson A, Nyqvist K, Heurgren M. Kvalitet och innehåll i patientregistret. Utskrivningar från slutenvården 1964–2007 och besök i specialiserad öppenvård (exklusive primärvårdsbesök) 1997–2007. Stockholm: Socialstyrelsen; 2008. Accessed 02 May 2024.

  • Rizzardi K, Noren T, Aspevall O, Makitalo B, Toepfer M, Johansson A, et al. National Surveillance for Clostridioides difficile Infection, Sweden, 2009–2016. Emerging infectious diseases. 2018;24(9):1617–25 PubMed PMID: 30124193. Pubmed Central PMCID: PMC6106436. Epub 2018/08/21.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Marra AR, Perencevich EN, Nelson RE, Samore M, Khader K, Chiang HY, et al. Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(1):e1917597. PubMed PMID: 31913488. Pubmed Central PMCID: PMC6991241. Epub 2020/01/09.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Socialstyrelsen. The Swedish Prescribed Drug Register 2020 [updated 21–8–202130–9–2021]. Available from: https://www.socialstyrelsen.se/en/statistics-and-data/registers/register-information/the-swedish-prescribed-drug-register/.

  • Brusselaers N, Lagergren J. Maintenance use of non-steroidal anti-inflammatory drugs and risk of gastrointestinal cancer in a nationwide population-based cohort study in Sweden. BMJ Open. 2018;8(7): e021869.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Socialstyrelsen;. The Causes of Death Register 2018 [updated 2019–05–29]. Available from: https://www.socialstyrelsen.se/statistik-och-data/register/dodsorsaksregistret/bortfall-och-kvalitet/.

  • Cançado GGL, Abreu ES, Nardelli MJ, Serwa P, Brachmann M. A cost of illness comparison for toxigenic Clostridioides difficile diagnosis algorithms in developing countries. Anaerobe. 2021;70:102390. PubMed PMID: 34058377. Epub 2021/06/01. eng.

    Article 
    PubMed 

    Google Scholar 

  • Yu H, Alfred T, Nguyen JL, Zhou J, Olsen MA. Incidence, Attributable Mortality, and Healthcare and Out-of-Pocket Costs of Clostridioides difficile Infection in US Medicare Advantage Enrollees. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023;76(3):e1476–83 PubMed PMID: 35686435. Pubmed Central PMCID: PMC9907506. Epub 2022/06/11. eng.

    Article 
    PubMed 

    Google Scholar 

  • Wilcox MH, Ahir H, Coia JE, Dodgson A, Hopkins S, Llewelyn MJ, et al. Impact of recurrent Clostridium difficile infection: hospitalization and patient quality of life. The Journal of antimicrobial chemotherapy. 2017;72(9):2647–56 PubMed PMID: 28633368. Epub 2017/06/22. eng.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Paschos P, Ioakim K, Malandris K, Koukoufiki A, Nayfeh T, Akriviadis E, et al. Add-on interventions for the prevention of recurrent Clostridioides Difficile infection: A systematic review and network meta-analysis. Anaerobe. 2021;71:102441. PubMed PMID: 34454094. Epub 2021/08/29. eng.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Richardson M, Erman A, Daneman N, Miller FA, Sander B. Defining the decision problem: a scoping review of economic evaluations for Clostridioides difficile interventions. The Journal of hospital infection. 2022;121:22–31 PubMed PMID: 34813872. Epub 2021/11/24. eng.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Gupta A, Ananthakrishnan AN. Economic burden and cost-effectiveness of therapies for Clostridiodes difficile infection: a narrative review. Therap Adv Gastroenterol. 2021;14:17562848211018654 PubMed PMID: 34104214. Pubmed Central PMCID: PMC8170348. Epub 2021/06/10. eng.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Swart N, Sinha AM, Bentley A, Smethurst H, Spencer G, Ceder S, et al. A cost-utility analysis of two Clostridioides difficile infection guideline treatment pathways. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2023;29(10):1291–7 PubMed PMID: 37356620. Epub 2023/06/26. eng.

    Article 
    PubMed 

    Google Scholar 

  • link

    Leave a Reply

    Your email address will not be published. Required fields are marked *